Author

Andrew Friedl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Deborah Manst· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

Computational Structural Analysis of POLG Variants R627Q and W748S with Model-Variability Controls

Andrew Friedl, Deborah Manst

This paper evaluates structural changes in POLG variants R627Q and W748S using AlphaFold2 models and experimental structures, finding no clear mutation-specific deformation but suggesting physicochemical hypotheses.

bioRxiv · Aug 27, 2026 · PreprintBiophysics