Exosomal TAR DNA binding protein 43 profile in canine model of amyotrophic lateral sclerosis: A preliminary study in developing blood-based biomarker for neurodegenerative diseases
Penelope Pfeiffer, Joan R. Coates, Yajaira M. Esqueda, Andrew Kennedy, Kyleigh Getchell, Myra McLenon, Edina Kosa, Abdulbaki Aǵbaş
This study identifies exosomal TDP-43 as a potential biomarker in canine degenerative myelopathy, suggesting serum-derived exosomes could serve as a non-invasive tool for neurodegenerative disease biomarker development.
Annals of Medicine · Dec 10, 2022Peer-reviewedNeuroscience