A Quantitative Analysis of Localized Robustness of MYCN in Neuroblastoma
Romeil Sandhu, Sarah Tannenbaum, Daniel Diolaiti, Alberto Ambesi-Impiombato, Andrew Kung, Allen Tannenbaum
This paper uses network curvature to show that MYCN amplification in neuroblastoma correlates with higher biological robustness, suggesting new indirect targeting strategies.
bioRxiv · Jan 22, 2016 · PreprintCancer Biology