THRESHER: A tool for evidence-based, phylogeny-corrected SNP thresholds for whole genome molecular epidemiology
Qianxuan She, Andries Feder, Erin Theiller, Joseph P. Zackular, Ahmed M. Moustafa, Paul Joseph Planet
THRESHER calculates data-driven SNP thresholds for bacterial genomes to improve strain classification compared to fixed cutoffs.
medRxiv · Oct 11, 2026 · PreprintGenetic & Genomic Medicine