Integrated histopathologic modeling of detailed tumor subtypes and actionable biomarkers
Kevin M Boehm, Madison Darmofal, Arfath Pasha, Andrew T. Aukerman, Raymond S. Lim, Evan Seffar, Tom Pollard, Natasha Rekhtman, Jason C. Chang, Armaan Kohli, Darin Moore, Marta Ligero, Jianjiong Gao, Georgios Asimomitis, Anika Begum, , Francisco Sánchez-Vega
The paper develops Mosaic, a machine learning system that classifies tumors into detailed subtypes and identifies molecular phenotypes using histopathologic and genomic data from a large patient cohort.
bioRxiv · Aug 14, 2025 · PreprintCancer Biology