Contextualising the developability risk of antibodies with lambda light chains using enhanced therapeutic antibody profiling
Matthew I. J. Raybould, Oliver M. Turnbull, Annabel Suter, Bora Guloglu, Charlotte Mary Deane
The paper updates a tool to assess developability risks of kappa and lambda antibodies using machine learning, finding lambda antibodies have higher risk but some are more tractable.
Communications Biology · Jan 8, 2024Peer-reviewedBioinformatics