Haplotype-Resolved Long-Read Sequencing in Hundreds of Diverse Brains Identifies Structural Variant Impacts on Expression and Allele-Specific Methylation
Melissa Meredith, Kensuke Daida, Abraham Moller, Pilar Álvarez Jerez, Shloka Negi, Laksh Malik, Rylee M. Genner, Xinchang Zheng, Sophia B Gibson, Mira Mastoras, Breeana Baker, Cedric Kouam, Kimberly Paquette, Paige Jarreau, Mary B. Makarious, , Kimberley J. Billingsley
The paper uses long-read sequencing to identify structural variants and their impacts on gene expression and methylation in diverse human brain samples.
bioRxiv · Dec 16, 2024 · PreprintGenomics