Long-read sequencing reveals the RNA isoform repertoire of neuropsychiatric risk genes in human brain
Ricardo De Paoli‐Iseppi, Shweta S Joshi, Josie Gleeson, Yair D. J. Prawer, Yupei You, Ria Agarwal, Anran Li, Anthea Hull, Eloise Marie Whitehead, Yoonji Seo, Rhea Kujawa, Raphael Chang, Mriga Dutt, Catriona McLean, Benjamin L. Parker, Michael B. Clark
The paper uses long-read sequencing to identify novel RNA isoforms in neuropsychiatric risk genes, revealing previously undetected exons and isoforms that may contribute to disease mechanisms.
Genome biology · Sep 23, 2025Peer-reviewedGenetic & Genomic Medicine