Neuronal Activity-Dependent Electroosmosis and Its Potential Role in Interstitial Fluid Flow in the Glymphatic System
Parnian Hemmati, Anthony C. Wang, Mayumi L. Prins, Christopher C. Giza, Pirouz Kavehpour
This paper proposes electroosmosis as a mechanism for interstitial fluid flow in the brain, showing it generates realistic velocities and explains glymphatic transport differences between sleep and wakefulness.
bioRxiv · Jun 18, 2026 · PreprintBioengineering