Author

Antoine Maechler

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dianzhuo WangiD· 1 shared Eugene I. ShakhnovichiD· 1 shared Jonathan D. FeldmaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Dianzhuo WangORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

A General Framework for Injecting BiophysicalPriors into Protein Embeddings

Jonathan D. Feldman, Antoine Maechler, Dianzhuo Wang, Eugene I. Shakhnovich

This paper introduces a framework that integrates biophysical priors into protein embeddings to improve DeltaDeltaG prediction, showing that general-purpose encoders can outperform specialized models.

bioRxiv · Feb 23, 2026 · PreprintBioinformatics