Evaluation of haplotype callers for next-generation sequencing of viruses
Anton Eliseev, Keylie M. Gibson, Pavel Avdeyev, D. K. Novik, Matthew L. Bendall, Marcos Pérez‐Losada, Nikita Alexeev, Keith A. Crandall
This study evaluates twelve haplotype callers for NGS viral sequencing, finding they perform poorly under high genetic diversity, with PredictHaplo and PEHaplo showing better accuracy for HIV-like diversity levels.
Infection Genetics and Evolution · Mar 6, 2020Peer-reviewedBioinformatics