Exploring the energy landscape of bacterial chromosome segregation
Sumitabha Brahmachari, Antonio B. Oliveira, Matheus F. Mello, Vinícius G. Contessoto, José N. Onuchic
The paper develops an energy-landscape framework to study bacterial chromosome segregation, showing SMC complexes enable a mid-replication transition crucial for faithful segregation.
Proceedings of the National Academy of Sciences · Mar 17, 2026Peer-reviewedBiophysics