The Nrf2/Id2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging
Mulin Xu, Xiuxian Wei, Jinli Wang, Yi Li, Yi Huang, Anying Cheng, Fan He, Le Zhang, Cuntai Zhang, Yu Liu
This study investigates the role of NRF2 in vascular calcification and aging, finding that NRF2 dysfunction contributes to vascular smooth muscle cell senescence and calcification, with ID2 as a downstream regulator.
Aging and Disease · May 23, 2024Peer-reviewedMolecular Biology