SiRNA Molecules as Potential RNAi Therapeutics to Silence RdRP Region and N-Gene of SARS-CoV-2: An In Silico Approach
Mahedi Hasan, Atiya Tahira Tasnim, Arafat Islam Ashik, Md. Belal Chowdhury, Zakia Sultana Nishat, Khandaker Atkia Fariha, Tanvir Hossain, Shamim Ahmed
The paper develops a computational approach to predict siRNAs targeting SARS-CoV-2 RdRp and N-gene, identifying 4 and 3 candidates respectively that show potential across variants.
bioRxiv · Oct 8, 2022 · PreprintBioinformatics