The fate of mutations on Y chromosomes andautosomes: a unified Wright-Fisher frameworkaccounting for segregation time
Ariel Offenstadt, Sylvain Billiard, Tatiana Giraud, Amandine Véber, Paul Jay
This study develops a unified Wright-Fisher model to analyze mutation fate on Y chromosomes and autosomes, showing overdominant mutations are more likely to fix on Y chromosomes due to segregation time effects.
bioRxiv · Apr 3, 2026 · PreprintEvolutionary Biology