mRNA destabilisation through CDS-targeting is the primary role of endogenous miRNA in the green alga Chlamydomonas.
Betty Chung, Michael J. Deery, Arnoud J. Groen, Julie Howard, David C. Baulcombe
The paper shows that in Chlamydomonas, miRNAs mainly destabilize mRNAs, with target sites in coding regions, differing from metazoan systems.
Nature Plants · Oct 2, 2017Peer-reviewedMolecular Biology