Causal feature selection using a knowledge graph combining structured knowledge from the biomedical literature and ontologies: a use case studying depression as a risk factor for Alzheimer's disease
Scott A. Malec, Sanya B. Taneja, Steven M. Albert, C. Elizabeth Shaaban, Helmet Talib Karim, Arthur S. Levine, Paul Munro, Tiffany J. Callahan, Richard D. Boyce
This paper introduces a knowledge graph approach to causal feature selection, identifying confounders, mediators, and colliders for depression's effect on Alzheimer's disease risk.
Journal of Biomedical Informatics · Apr 21, 2023Peer-reviewedSystems Biology