Evaluation of machine learning methods to predict peptide binding to MHC Class I proteins
Rohit Bhattacharya, Ashok Sivakumar, Collin J. Tokheim, Violeta Beleva Guthrie, Valsamo Anagnostou, Victor E. Velculescu, Rachel Karchin
This study evaluates machine learning methods for predicting peptide-MHC Class I binding affinities, finding that MHCnuggets performs similarly to existing methods but is faster and handles variable-length peptides.
bioRxiv · Jul 27, 2017 · PreprintBioinformatics