A minimal model demonstrates the control of mouse sperm capacitation by a positive feedback loop between sNHE and SLO3
B. de Prelle, D. Gall, P. Lybaert
The paper develops a mathematical model showing that a positive feedback loop between SLO3 and sNHE controls mouse sperm capacitation, explaining bistability and predicting SLO3 inhibition as a potential therapeutic target.
bioRxiv · Nov 30, 2021 · PreprintCell Biology