Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling
B. El Houdaigui, R. Forquet, T. Hindre, D. Schneider, W. Nasser, S. Reverchon, S. Meyer
The paper models how DNA supercoiling affects transcription in bacteria and shows that global gene orientation influences supercoiling sensitivity.
bioRxiv · Feb 27, 2019Microbiology