Evolutionary history of Alzheimer Disease causing protein family Presenilins with pathological implications.
A. A. Khan, B. Parveen, H. A. Raja
This study investigates the evolutionary history of Presenilins, showing they originated in the last common eukaryotic ancestor and are under strong purifying selection, with mutations linked to Alzheimer's disease.
bioRxiv · Aug 20, 2018Evolutionary Biology