Determining the Quantitative Principles of T Cell Response to Antigenic Disparity: The Case of Stem Cell Transplant Donor-Recipient Exome Wide Mismatching and HLA Bound Alloreactive Peptides
Ali Salman, Vishal Koparde, Charles Hall, Max Jameson-Lee, Catherine Roberts, Myrna Serrano, Badar AbdulRazzaq, Masoud Manjili, Dayanjan Wijesinghe, Shahrukh Hashmi, Greg Buck, Rehan Qayyum, Michael Neale, Jason Reed, Amir Toor
The paper quantifies T cell responses to alloreactive peptides in stem cell transplantation using exome-wide data and a tensor-based framework to predict alloreactive complications.
bioRxiv · Apr 21, 2018 · PreprintImmunology