Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitors
Jing Zhou, Miguel Flores‐Bellver, Jianbo Pan, Alberto Benito‐Martín, Cui Shi, Onyekwere Onwumere, Jason Mighty, Jiang X. Qian, Xiufeng Zhong, Tasmim Hogue, Baffour Amponsah-Antwi, Linda Saxe Einbond, Rajendra Gharbaran, Hao Wu, Bo‐Juen Chen, , Stephen Redenti
This study identifies EVs from human retinal organoids and shows they regulate gene expression in retinal progenitors through miRNA cargo.
Scientific Reports · Oct 26, 2021Peer-reviewedDevelopmental Biology