Cellf-Deception: Human microglia clone 3 (HMC3) cells exhibit more astrocyte-like than microglia-like gene expression
Kylee K. Rahm, Branden S. Kinghorn, Myanna J. Moody, Ben C. Stone, Kaitlyn Strong, Brian S. Kim, Yen Jou Chang, Samantha Sleight, Alyssa A. Nitz, David V. Hansen, Matthew H. Bailey
The paper shows that HMC3 cells are more astrocyte-like than microglia-like, suggesting they are not a reliable microglia model.
Frontiers in Bioinformatics · Nov 4, 2025Peer-reviewedNeuroscience