Genome-wide association study provides novel insight into the genetic architecture of severe obesity.
Mohanraj Krishnan, Mohammad Yaser Anwar, Anne E. Justice, Geetha Chittoor, Hung‐Hsin Chen, Rashedeh Roshani, Alyssa Scartozzi, Rachel R. Dickerson, Roelof A. J. Smit, Michael H Preuss, Nathalie Chami, Benjamin S Hadad, Esteban Juan Parra, Miguel Cruz, Qin Hui, , Mariaelisa Graff
This study identifies novel genetic signals associated with severe obesity through GWAS and shows strong genetic overlap with BMI, highlighting shared comorbidities and lifestyle interactions.
PLoS Genetics · Sep 12, 2025Peer-reviewedGenetic & Genomic Medicine