So ManyFolds, So Little Time: Efficient Protein Structure Prediction With pLMs and MSAs
Thomas D. Barrett, Amelia Villegas-Morcillo, Louis Robinson, Benoit Gaujac, David Adméte, Elia Saquand, Karim Beguir, Arthur Flajolet
The paper presents a streamlined AlphaFold variant using pLMs and MSAs, showing that combining or using either modality achieves comparable performance to models trained exclusively on one.
bioRxiv · Oct 15, 2022 · PreprintBioinformatics