Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics
René Breuer, Manuel Mattheisen, Josef Frank, Bertram Krumm, Jens Treutlein, Layla Kassem, Jana Strohmaier, Stefan Herms, Thomas W. Mühleisen, Franziska Degenhardt, Sven Cichon, Markus Maria Nöthen, George Karypis, Francis J. McMahon, Marcella Rietschel, Thomas G. Schulze
The paper applies association rule mining to GWAS data of bipolar disorder to identify novel genotype-phenotype relationships not detected by traditional GWAS methods.
bioRxiv · Mar 14, 2017 · PreprintGenomics