Sex and insulin resistance biomarker modelling in a new large-scale Alzheimer's disease transcriptomic resource
Nasim Mohamed Ismail, Maggie A. Miller, Hannah Crossland, Bethan E Phillips, Jalil-Ahmad Sharif, Christina Kosanovic, Tianjie Gu, Robert J Brogan, Claes Wahlestedt, Philip J Atherton, J. Paul Chapple, William E Kraus, Kirill Shkura, Anthony J Griswold, Claude‐Henry Volmar, , James A. Timmons
The paper develops a large-scale blood transcriptomic resource for Alzheimer's disease, identifies sex-specific differences, and models insulin resistance biomarkers using machine learning.
medRxiv · Oct 2, 2025 · PreprintGenetic & Genomic Medicine