Aberrant accumulation of α-synuclein might be linked with the progressive motor deficits in a mouse model of Angelman syndrome
Sagarika Das, Bhaskarjyoti Giri, Nihar Ranjan Jana
This study links aberrant α-synuclein accumulation to motor deficits in an Angelman syndrome mouse model, showing Ube3a's role in its degradation and identifying dopamine/serotonin pathway gene alterations.
bioRxiv · Sep 3, 2026 · PreprintNeuroscience