Quantifying Molecular Bias in DNA Data Storage
Yuan-Jyue Chen, Christopher N. Takahashi, Lee Organick, Callista Bee, Siena Dumas Ang, Patrick Weiss, Bill J. Peck, Georg Seelig, Luís Ceze, Karin Strauß
This paper quantifies molecular bias in DNA data storage by analyzing synthesis and PCR processes, identifying their contributions to copy number unevenness and proposing a statistical model to optimize storage efficiency.
Nature Communications · Jun 29, 2020Peer-reviewedSynthetic Biology