An entropy-based diagnostic framework for characterizingmethylation state dynamics during preimplantation development
Bingjie Hao, Yuxiang Cheng, Zhiyuan Liu
The paper develops a computational framework to analyze methylation state dynamics during preimplantation development and identifies the morula stage as a key point for age-associated methylation features.
bioRxiv · Aug 26, 2026 · PreprintDevelopmental Biology