Annotation-Free Deep Learning for Predicting Gene Mutations from Whole Slide Images of Acute Myeloid Leukemia
Bo-Han Wei, Xavier Cheng-Hong Tsai, Kuo-Jui Sun, Min‐Yen Lo, Sheng‐Yu Hung, Wen‐Chien Chou, Hwei‐Fang Tien, Hsin‐An Hou, Chien‐Yu Chen
This paper introduces a deep learning model using multiple instance learning to predict gene mutations from whole slide images of AML without manual annotations, achieving high AUC scores for NPM1 and FLT3-ITD mutations.
npj Precision Oncology · Feb 3, 2025Peer-reviewedBioinformatics