Characterizing cytosine methylation of polymorphic human transposable element insertions using human pangenome resources
Xiaoyu Zhuo, Chad Tomlinson, Edward A. Belter, Prashant Kumar Kuntala, Wesley N. Saintilnord, Juan Jiang, Tina A. Graves-Lindsay, Juan F Macias-Velasco, Bob S. Fulton, Ting Wang
The paper investigates methylation patterns of polymorphic transposable elements using long-read sequencing and the Human Pangenome Reference, revealing distinct methylation profiles and context-dependent interactions.
Genome Research · Jun 1, 2026Peer-reviewedBioinformatics