Reconstructing whole-organism cell phylogenies with resolved ancestral transcriptional states
Zhan Liu, Shanjun Deng, Mengdong Zhang, Boliang Liu, Huimin Xiang, Zhiyun Chen, Ao Zhang, Jay Shendure, Xionglei He
This paper reconstructs whole-organism cell phylogenies with resolved ancestral transcriptional states in zebrafish larvae using a novel computational framework called LEAP.
bioRxiv · Aug 2, 2026 · PreprintDevelopmental Biology