Stable networks of water-mediated interactions are conserved in activation of diverse GPCRs
A. J. Venkatakrishnan, Anthony K. Ma, Rasmus Fonseca, Naomi R. Latorraca, Brendan Kelly, Robin M. Betz, Chaitanya Asawa, Brian K. Kobilka, Dror Ron O.
The paper identifies conserved water-mediated interaction networks in GPCR activation across diverse receptors, with implications for drug design.
bioRxiv · Jun 20, 2018 · PreprintBiophysics