Author

Brenely V. Murillo

King Edward Memorial Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alexandra GrovesiD· 1 shared Allan D. SpigelmaniD· 1 shared Ana Beatriz Deleame MedeirosiD· 1 shared Aung Ko WiniD· 1 shared Bernard J. PopeiD· 1 shared Christophe RostyiD· 1 shared Daniel D. BuchananiD· 1 shared Emma Healey· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alexandra GrovesORCID

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1 paper

Recent·Most cited

Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications

Romy Walker, Jihoon Eric Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan Preston, Sharelle L. Joseland, Bernard J. Pope, Ana Beatriz Deleame Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin M. Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, , Peter Georgeson

The paper shows adenomas from individuals with biallelic MUTYH or NTHL1 variants have mutational signatures similar to CRCs, suggesting adenomas can be used for variant classification and cancer prevention.

medRxiv · Aug 8, 2024 · PreprintGenetic & Genomic Medicine