Thermodynamic modeling of Csr/Rsm- RNA interactions capture novel, direct binding interactions across the Pseudomonas aeruginosa transcriptome
Alexandra J. Lukasiewicz, Abigail N. Leistra, Lily Hoefner, Erika Monzon, Cindy J. Gode, Bryan Zorn, Kayley H. Janssen, Timothy L. Yahr, Matthew C. Wolfgang, Lydia M. Contreras
This study uses thermodynamic modeling to predict RsmA-mRNA binding interactions in Pseudomonas aeruginosa, identifying 1043 interactions including 457 novel targets, validated through experimental assays.
bioRxiv · Aug 1, 2024 · PreprintBioinformatics