A hierarchical regulatory cascade defines the temporal window of natural transformation in Staphylococcus aureus
Pierre Poirette, Shi Yuan Feng, Yolande Hauck, Yannis Arab, Sophie Quevillon‐Chéruel, Stéphanie Marsin, RIGOT Marine, Macha Dussouchaud, Roza Mohammedi, HAINAUT Thomas, BUDISAVLJEVIC Paul, Nicolas Mirouze
This paper identifies a hierarchical regulatory cascade in Staphylococcus aureus that defines the temporal window for natural transformation by linking environmental and metabolic cues to gene expression.
bioRxiv · Aug 4, 2026 · PreprintMicrobiology