Author

C. A. Sibbald

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Biophysics· 1

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

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G. R. Bowman· 1 shared J. R. Porter· 1 shared K. E. Moeder· 1 shared K. M. Hart· 1 shared M. I. Zimmerman· 1 shared M. J. Greenberg· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

G. R. Bowman

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1 paper

Recent·Most cited

Cooperative changes in solvent exposure identify cryptic pockets, conformational switches, and allosteric coupling

J. R. Porter, K. E. Moeder, C. A. Sibbald, M. I. Zimmerman, K. M. Hart, M. J. Greenberg, G. R. Bowman

The paper introduces a method to identify functionally-relevant conformational changes in proteins by analyzing cooperative solvent exposure changes, demonstrating its utility in discovering cryptic allosteric sites.

bioRxiv · Sep 18, 2018Biophysics