Adaptation of a Mutual Exclusivity Framework to Identify Driver Mutations within Biological Pathways
X. Wang, C. Kostrzewa, A. Reiner, R. Shen, C. Begg
The paper introduces MAGPIE, a computational method to identify driver mutations in cancer pathways by analyzing mutual exclusivity patterns, and validates it on melanoma data.
bioRxiv · Sep 19, 2023 · PreprintCancer Biology