COVID-19 and Cholinergic Anti-inflammatory Pathway: In silico Identification of an Interaction between alpha7 Nicotinic Acetylcholine Receptor and the Cryptic Epitopes of SARS-CoV and SARS-CoV-2 Spike Glycoproteins
G. Lagoumintzis, C. Chasapis, N. Alexandris, S. Tzartos, E. Eliopoulos, K. Farsalinos, K. Poulas
This study identifies molecular interactions between SARS-CoV and SARS-CoV-2 Spike glycoproteins and the alpha7 nicotinic acetylcholine receptor using in silico modeling and docking.
bioRxiv · Aug 20, 2020Immunology