Structural Insights into Hearing Loss Genetics from Polarizable Protein Repacking
M. R. Tollefson, J. Litman, G. Qi, R. J. Marini, C. E. O'Connell, M. J. Wipfler, H. V. Bernabe, W. T. Tollefson, T. L. Casavant, T. A. Braun, R. J. Smith, M. J. Schnieders
This study improves the structural resolution of deafness-associated proteins using polarizable force fields and shows how these data can enhance pathogenicity prediction.
bioRxiv · Feb 21, 2019Biophysics