C. H. Mak

A Deep Dive into DNA Base Pairing Interactions Under Water

This study uses Monte Carlo simulations to analyze how water molecules affect the free energy of DNA base pairing, showing that solvent resistance is more significant for G|C than A|T pairs.

Diagrammatic Theory of RNA Structures and Ensembles with Trinucleotide Repeats

This paper develops a diagrammatic theory to analyze the structural diversity of (CNG)n RNA sequences, showing that their ensembles are highly diverse and susceptible to perturbations.

Quantifying Structural Diversity of CNG Trinucleotide Repeats Using Diagrammatic Algorithms

This paper quantifies the structural diversity of CNG trinucleotide repeats using diagrammatic algorithms and finds that expanded RNA transcripts may adopt more open and less structured conformations than previously assumed.