Graph attention with structural features improves the generalizability of identifying functional sequences at a protein interface
J. Ash, Irené M. Francino-Urdaniz, Siobhan P. Kells, C. N. Davis, Timothy A. Whitehead, Sagar D. Khare
The paper improves prediction of functional protein interface sequences by integrating structural and sequence features using a graph attention model, achieving better generalization across diverse variants.
bioRxiv · Nov 4, 2025 · PreprintBiochemistry