Plasma endocannabinoids in cocaine dependence and their interaction with cocaine craving and metabotropic glutamate receptor 5 density in the human brain
Sara Liane Kroll, Lea M. Hulka, Ann-Kathrin Kexel, Matthias Vonmoos, Katrin H. Preller, Valérie Treyer, Simon Mensah Ametamey, Markus R. Baumgartner, Carola Boost, Franziska Pahlisch, Cathrin Rohleder, F. Markus Leweke, Boris B. Quednow
The paper investigates plasma endocannabinoids in cocaine dependence and their relationship with mGluR5 density in the brain, finding higher 2-AG levels in dependent users and a positive association with mGluR5 density.
bioRxiv · Apr 18, 2023 · PreprintNeuroscience