Synthetic Lethality Screening with Recursive Feature Machines
Cathy Cai, Adityanarayanan Radhakrishnan, Caroline Uhler
The paper develops a pipeline using Recursive Feature Machines to identify synthetic lethal gene pairs from CRISPR viability data, improving accuracy over prior methods and discovering new candidates.
bioRxiv · Dec 3, 2023 · PreprintBioinformatics