An evaluation of methods correcting for cell type heterogeneity in DNA methylation studies
Kevin McGregor, Sasha Bernatsky, Ines Colmegna, Marie Hudson, Tomi Pastinen, Aurélie Labbe, Celia Greenwood
The paper evaluates methods for correcting cell-type heterogeneity in DNA methylation studies and recommends surrogate variable analysis for its consistent performance.
Genome Biology · Dec 1, 2016Peer-reviewedBioinformatics