Targeting Oncogenic Mutations in Colorectal Cancer using Cryptotanshinone
Haswanth Vundavilli, Aniruddha A. Datta, Chao Sima A, Jianping Hua, Rosana Lopes, Michael L. Bittner
The paper identifies oncogenic mutations in colorectal cancer, constructs pathways, and uses boolean modeling to find effective drug combinations, validating results with wet lab experiments.
PLoS ONE · Feb 17, 2021Peer-reviewedSystems Biology