DNA Methylation Drives Aberrant Osteochondrogenesis in Keloid and Is Reversible by Decitabine
Lian Zhang, Chenmei Liu, Xinyuan Zhou, Yan Zhang, Renliang He, Ziyan Li, Shuqing Zhao, Cheng‐Cheng Deng, Hongtao Li, Bin Yang
This study identifies DNA methylation as a driver of aberrant osteochondrogenesis in keloids and shows that decitabine can reverse this epigenetic state.
bioRxiv · Aug 31, 2026 · PreprintCancer Biology