Mapping of genotype-by-environment interaction loci for Metabolic Syndrome-like traits using the multi-parent Drosophila Synthetic Population Resource determines that main genetic effects are distinct from environment dependent plastic loci
Kelly Dew-Budd, Ravi Mathur, Siddharth Roy, Julie Jarnigan, Andrea Moss, Andrei Bombin, Vishal H. Oza, Chinmay P Rele, Alison Adams, Sean Mendez, Katherine Bray, D. Gale Davis, Matthew B. Kieffer, Leah Leonard, Joana Hubickey, , Laura K Reed
This study identifies genetic loci for MetS-like traits in Drosophila and finds that main genetic effects are distinct from diet-dependent plastic loci.
bioRxiv · Aug 4, 2025 · PreprintGenetics